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Ph.D in Supercritical Chromatography Hyphenated with Hyperpolarised NMR (The Netherlands) Deadline: Aug 12, 2018

Institute for Materials and Molecules

The Faculty of Science, Radboud University

Application Deadline

August 12, 2018

Duration of the Program

1.5 to 4 Years

Program Details

Radboud University Nijmegen is a public university with a strong focus on research, located in Nijmegen, the Netherlands. As a Ph.D candidate of the solid-state NMR group of the Institute for Materials and Molecules, you will work within an ongoing project. The Ph.D position is funded by the Dutch science foundation NWO via Top Institute COAST (www.ti-coast.com). In this project two academic groups and three industrial partners cooperate. The combination of academic groups specializing in NMR methodology developments (RU Nijmegen) and separation methodology (UvA), and Bruker and Waters who are the dominating technology providers in the respective NMR and SFC fields, together with Shell as a potential end user of the technology makes a strong consortium to come up with a viable SFC-NMR approach.

The main goal of the project is to develop and optimize a hyphenated setup combining supercritical chromatography with DNP-NMR to provide a fast analytical tool to study complex mixtures with superior information content. At present a Gyrotron mm-wave source operating at 395 GHz is available for this purpose, coupled to a 600 MHz NMR spectrometer and a 263 GHz klystron (EIO) coupled to a 400 MHz NMR spectrometer. These setups will be developed further in this project, particularly in terms of probe technology and NMR approach. The general mission of the NMR group is to develop new methodology to optimize sensitivity and information content of NMR spectra and to apply these methods to target-specific topics in functional molecular systems in terms of local structure and dynamics addressing structure-function relationships. The institute offers stimulating and exciting international research environment with state-of-the-art NMR spectrometers.

Descriptions & Requirements

Read Supercritical Fluid Chromatography: Advances and Applications in Pharmaceutical Analysis that provides a comprehensive overview of the use of SFC in pharmaceutical analysis!

Applicants should meet the following requirements:

  • Hold an M.Sc. in Chemistry or Physics or a related discipline;
  • Be an enthusiastic candidate with a solid background in physical chemistry and with an affinity for out-of-the-box methodology development.

The selected candidate will be offered:

  • a maximum gross monthly salary of € 2,897 based on a 38-hour working week.
  • the gross starting salary amounts to €2,266 per month, and will increase to €2,897 in the fourth year (P scale).
  • in addition to the salary: an 8% holiday allowance and an 8.3% end-of-year bonus.

The appointment is for an initial period of 18 months, after which your performance will be evaluated. If the evaluation is positive, the contract will be extended by 2.5 years.

Application Process

To apply, click here (Vacancy number: 62.58.18)

You should upload your application along with (and be limited to) the following attachment(s):

  • Letter of motivation
  • CV

For more information about the call, click here.

For queries and clarifications, please contact Prof. Dr. A.P.M. Kentgens, Telephone: +31 24 3652078, E-mail: a.kentgens@nmr.ru.nl and/ or M.C. de With, Secretary – Solid State NMR, Telephone: +31 24 3652678, E-mail: m.dewith@nmr.ru.nl

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